We decode the complete molecular chain from genotype to proteotype — mapping how every genetic variant shapes protein structure, modifications, interactions, and function.
For decades, we sequenced genomes and measured transcripts, believing RNA would tell us everything about cellular function. It doesn't. Post-transcriptional regulation, translational control, and post-translational modifications create a proteome orders of magnitude more complex than the genome.
Proteins are the true molecular machines of life — the workhorses that execute virtually every function in every cell, from catalysis to signalling to structural integrity.
Not predictions. Direct, measurable, actionable protein phenotypes.
Proteins execute virtually every function necessary for life. Their remarkable structural diversity enables thousands of distinct biochemical roles.
Comprehensive approaches to understanding the genotype-to-proteotype relationship across computation, structure, and clinical translation.
An interdisciplinary collective building the foundations of a new scientific field, from microbiology and data science to biotechnology.
We are building a new scientific discipline from the ground up. We need passionate researchers, engineers, and visionaries who believe that understanding protein biology at molecular resolution will transform medicine.
Whether you are a computational biologist, structural biologist, proteomics specialist, or deeply curious newcomer — if you can contribute to mapping the genotype-to-proteotype landscape, we want to hear from you.
Questions? Ideas? Collaborations? We'd love to hear from you.